What Is Tesamorelin?
Tesamorelin is a synthetic 44-residue peptide analog of human growth hormone-releasing hormone, commonly abbreviated GHRH.
It incorporates a defined N-terminal modification while retaining a GHRH-derived peptide sequence.
PubChem identifies Tesamorelin as CAS 218949-48-5, PubChem CID 16137828, molecular formula C221H366N72O67S, molecular weight approximately 5136 g/mol, and research identifier TH9507.
Tesamorelin at a Glance
| Attribute | Information |
|---|---|
| Name | Tesamorelin |
| Research identifier | TH9507 |
| Compound class | Synthetic GHRH analog |
| Sequence length | 44 residues |
| CAS | 218949-48-5 |
| PubChem CID | 16137828 |
| Formula | C221H366N72O67S |
| Molecular weight | ~5136 g/mol |
What Is GHRH?
Growth hormone-releasing hormone is a hypothalamic peptide that signals through the growth hormone-releasing hormone receptor, or GHRH-R.
GHRH-R belongs to the G-protein-coupled receptor family. Modern research continues to examine receptor activation, regulation, splice variants and intracellular signaling. A 2025 review specifically summarized current knowledge of GHRH-R molecular mechanisms and signaling pathways.
Why Is Tesamorelin Called a GHRH Analog?
An analog preserves important structural characteristics of another molecule while incorporating one or more defined modifications.
Tesamorelin retains the GHRH-derived 44-residue sequence while incorporating an N-terminal structural modification.
That distinction means Tesamorelin should not simply be treated as native GHRH.
What Does TH9507 Mean?
TH9507 is a research-development identifier associated with Tesamorelin and appears in PubChem and scientific literature.
Why Is Material Form Important?
Chemical databases separately represent Tesamorelin and Tesamorelin acetate.
This matters when researchers interpret:
- CAS number
- molecular weight
- molecular formula
- mass-spectrometric results
- Certificates of Analysis
Researchers should therefore match the chemical identity used in an experiment to the material form documented for the actual lot.
Current Scientific Context
Research involving GHRH now extends beyond classical endocrine studies.
A 2025 review emphasized newer receptor-specific tools, modern imaging approaches and tissue-specific experimental models used to study GHRH regulation and signaling.
Tesamorelin 10 mg Research Material
Research Information
Continue the Tesamorelin Research Cluster
View Tesamorelin 10 mg Research Material for the product-specific research-material page.
